Details
Quality products?make an important contribution to long-term revenue and profitability. Chinese factory supply 1,2,3,4-Tetrahydro-1-methylquinoline 491-34-9 in stock with high standard
1.What is the 1,2,3,4-Tetrahydro-1-methylquinoline ?
Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-1-methylquinoline is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs, particularly those targeting the central nervous system.
Used in Chemical Synthesis:
1,2,3,4-Tetrahydro-1-methylquinoline is used as a building block in the synthesis of complex organic molecules. Its versatile structure makes it a valuable precursor for the creation of a wide range of compounds, including those with potential applications in materials science, agrochemicals, and other specialized fields.
Used in Research and Development:
Due to its unique chemical properties, 1,2,3,4-Tetrahydro-1-methylquinoline is used in research and development for exploring new reactions and understanding the behavior of similar compounds. It can serve as a model for studying the effects of N-methyl substitution on the reactivity and stability of tetrahydroquinoline derivatives.
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-
3947-76-0
N-methylquinolinium iodide
-
-
491-34-9
N-methyl-1,2,3,4-tetrahydroquinoline
| Conditions | Yield |
|---|---|
|
With
tetrahydroxydiboron; potassium tert-butylate; water;
In
methanol;
at 60 ℃;
for 8h;
Inert atmosphere;
|
60%
|
|
With
hydrogen; cobalt(II) diacetate tetrahydrate; zinc;
In
methanol; water;
at 90 ℃;
for 15h;
under 22502.3 Torr;
Sealed tube;
Autoclave;
|
23%
|
|
With
hydrogenchloride; tin;
|
|
|
With
sodium hydroxide;
|
|
|
durch Reduktion;
|
|
|
With
ethanol; nickel; diethylamine;
at 140 ℃;
under 44130.5 Torr;
Hydrogenation;
|
|
|
With
ethanol; platinum;
Hydrogenation;
|
|
|
With
hydrogen;
platinum;
In
methanol;
Yield given;
|
-
-
635-46-1
1,2,3,4-tetrahydroisoquinoline
-
-
74-88-4
methyl iodide
-
-
491-34-9
N-methyl-1,2,3,4-tetrahydroquinoline
| Conditions | Yield |
|---|---|
|
1,2,3,4-tetrahydroisoquinoline;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
for 1h;
Inert atmosphere;
methyl iodide;
In
tetrahydrofuran; hexane;
at 20 ℃;
for 12h;
Inert atmosphere;
|
79%
|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane;
1.) THF, hexane, 0 deg C, 2.) 12 h, rt;
|
71%
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
for 0.5h;
methyl iodide;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 16h;
|
61%
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
for 0.5h;
methyl iodide;
In
tetrahydrofuran;
at 20 ℃;
|
61%
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
methyl iodide;
In
tetrahydrofuran;
at 0 - 20 ℃;
|
61%
|
|
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
|
61%
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
methyl iodide;
In
tetrahydrofuran;
at 20 ℃;
for 16h;
|
61%
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
methyl iodide;
at 20 ℃;
|
61%
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 5 ℃;
for 0.5h;
methyl iodide;
In
tetrahydrofuran;
at 0 - 20 ℃;
|
61%
|
|
With
sodium hydride;
In
tetrahydrofuran;
Inert atmosphere;
Cooling with ice;
|
56%
|
|
With
sodium hydride;
In
tetrahydrofuran;
for 15h;
Heating;
|
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
DMF (N,N-dimethyl-formamide);
at 0 ℃;
for 1h;
methyl iodide;
In
DMF (N,N-dimethyl-formamide);
at 0 - 20 ℃;
for 12h;
|
|
|
With
potassium carbonate;
In
acetone;
|
|
|
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 - 25 ℃;
for 12h;
Inert atmosphere;
Sealed tube;
|
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 ℃;
for 2h;
methyl iodide;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
|
|
|
1,2,3,4-tetrahydroisoquinoline;
With
sodium hydride;
In
tetrahydrofuran;
for 0.5h;
Cooling with ice;
methyl iodide;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
|
2.What is the CAS number for 1,2,3,4-Tetrahydro-1-methylquinoline ?
The CAS number of 1,2,3,4-Tetrahydro-1-methylquinoline is 491-34-9.
More information of 1,2,3,4-Tetrahydro-1-methylquinoline 491-34-9 are:
|
CAS?Number |
491-34-9 |
|
Density |
0.999 g/cm3 |
|
Melting Point |
114 °C |
|
Boiling Point |
248.3 °C at 760 mmHg |
|
Flash Point |
95 °C |
|
Vapor Pressure |
0.0244mmHg at 25°C |
|
Refractive Index |
1.5802 (estimate) |
|
HS CODE |
2933499090 |
|
PSA |
3.24000 |
|
LogP |
2.13400 |
|
Pka |
6.07±0.20(Predicted) |
3.What are another words for 1,2,3,4-Tetrahydro-1-methylquinoline ?
Synonyms?for?1,2,3,4-Tetrahydro-1-methylquinoline 491-34-9:Kairoline(6CI);1-Methyl-1,2,3,4-tetrahydroquinoline;Kairolin;Kuzol A;N-Methyl-1,2,3,4-tetrahydroquinoline;
4.What is the molecular formula of 1,2,3,4-Tetrahydro-1-methylquinoline?
The chemical formula of ?1,2,3,4-Tetrahydro-1-methylquinoline is?C10H13N which containing 10 Carbon atoms,13 Hydrogen atoms and 1 Nitrogen atoms,and the molecular weight of??1,2,3,4-Tetrahydro-1-methylquinoline?is 147.22.
5.What is 1,2,3,4-Tetrahydro-1-methylquinoline (491-34-9) used for?
1,2,3,4-Tetrahydro-1-methylquinoline is a tertiary amine derived from 1,2,3,4-tetrahydroquinoline with an N-methyl substituent. It is an organic compound with potential applications in various industries due to its unique chemical properties.
InChI:InChI=1/C10H13N/c1-11-8-4-6-9-5-2-3-7-10(9)11/h2-3,5,7H,4,6,8H2,1H3
Relevant articles related to 1,2,3,4-Tetrahydro-1-methylquinoline:
|
Article |
Source |
|
Access to gem-Difluoro Olefins via C-H Functionalization and Dual Role of Anilines |
Koenigs, Rene M.,Pei, Chao,Yang, Zhen , p. 7234 - 7238 (2020) |
|
Novel borane reduction of ether-protected aromatic lactams |
Hu, Wan-Ping,Tsai, Pei-Ching,Hsu, Ming-Kuan,Wang, Jeh-Jeng , p. 3983 - 3985 (2004) |
6.Buy 1,2,3,4-Tetrahydro-1-methylquinoline with the best price .
CHANGCHUN WEIERSI IMPORT AND EXPORT TRADE CO.,LTD is a quality supplier of 1,2,3,4-Tetrahydro-1-methylquinoline. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 1,2,3,4-Tetrahydro-1-methylquinoline 491-34-9.