Pharmaceutical

4-AMINO-2-METHYLQUINOLINE

  • CAS:6628-04-2
  • purity:99%
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1.What is the 4-AMINO-2-METHYLQUINOLINE ?

4-Amino-2-methylquinoline is used as a pharmaceutical intermediate.

4-chloro-2-methylquinoline
4295-06-1

4-chloro-2-methylquinoline

4-amino-2-methylquinoline
6628-04-2

4-amino-2-methylquinoline

Conditions
Conditions Yield
With 2-((dicyclohexylphosphino)methyl)-1,3-bis(2,6-diisopropylphenyl)-4,5-dimethyl-1H-imidazol-3-ium iodide; ammonia; palladium diacetate; sodium t-butanolate; In 1,4-dioxane; at 120 ℃; for 24h; under 7500.75 Torr; Autoclave; Inert atmosphere;
99%
With ammonia; C38H57ClNiP2; sodium t-butanolate; In 1,4-dioxane; at 65 ℃; for 18h; Reagent/catalyst; Glovebox;
95%
With bis(1,5-cyclooctadiene)nickel (0); (R)-1-[(Sp)-2-(dicyclohexylphosphanyl)ferrocenyl]ethyldicyclohexylphosphane; ammonia; sodium t-butanolate; In 1,4-dioxane; toluene; at 110 ℃; for 16h; Sealed tube;
80%
With ((+/-)-binap)Ni[P(OPh)3]2*2PhCH3; ammonia; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In 1,4-dioxane; at 120 ℃; for 18h; Inert atmosphere; Sealed tube;
46%
With ethanol; ammonia; at 200 ℃;
With acetamide; ammonia; phenol;
With ammonia; water; copper(II) sulfate;
Multi-step reaction with 2 steps
1: absolute alcohol; hydrazine hydrate
2: zinc-powder; aqueous H2 SO4
With ethanol; sulfuric acid; hydrazine hydrate; zinc;
With ammonia; palladium diacetate; sodium t-butanolate; 2-(di-tert-butyl-phosphino)-1-phenyl-1H-pyrrole; In 1,4-dioxane; at 120 ℃; for 24h; under 7500.75 Torr; Autoclave; Inert atmosphere;
> 99 %Chromat.
With 2-((dicyclohexylphosphino)methyl)-1,3-bis(2,6-diisopropylphenyl)-4,5-dimethyl-1H-imidazol-3-ium iodide; ammonia; palladium diacetate; sodium t-butanolate; In 1,4-dioxane; at 120 ℃; under 7500.75 Torr; Inert atmosphere; Autoclave;
98 %Chromat.
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 120 °C
2: ammonium cerium (IV) nitrate / acetonitrile / 5 h / 40 °C
With ammonium cerium (IV) nitrate; potassium carbonate; In N,N-dimethyl-formamide; acetonitrile;
Multi-step reaction with 2 steps
1: caesium carbonate / dimethyl sulfoxide / 4 h / 120 °C
2: ammonium cerium (IV) nitrate / acetonitrile / 5 h / 120 °C
With ammonium cerium (IV) nitrate; caesium carbonate; In dimethyl sulfoxide; acetonitrile;
Multi-step reaction with 2 steps
1: triethylamine / N,N-dimethyl-formamide / 4 h / 120 °C
2: palladium on activated charcoal; hydrogen / methanol / 6 h / 50 °C
With palladium on activated charcoal; hydrogen; triethylamine; In methanol; N,N-dimethyl-formamide;
Multi-step reaction with 2 steps
1: 2 h / 130 °C
2: trifluoroacetic acid / 2.5 h / 80 °C
With trifluoroacetic acid;
N,N-Diethyl-(2-methyl-4-chinolinyl)carbamidat
83842-18-6

N,N-Diethyl-(2-methyl-4-chinolinyl)carbamidat

4-amino-2-methylquinoline
6628-04-2

4-amino-2-methylquinoline

Conditions
Conditions Yield
With C43H60ClFeNNiP2; ammonia; sodium t-butanolate; In 1,4-dioxane; o-xylene; at 100 ℃; for 16h; Reagent/catalyst; Inert atmosphere; Autoclave;
89%
With (CyPFCy)Ni(o-tol)Cl; ammonia; sodium t-butanolate; In 1,4-dioxane; at 80 ℃; for 16h; Inert atmosphere; Sealed tube;
85%

2.What is the CAS number for 4-AMINO-2-METHYLQUINOLINE ?

The CAS number of 4-AMINO-2-METHYLQUINOLINE is 6628-04-2.

More information of 4-AMINO-2-METHYLQUINOLINE 6628-04-2 are:

CAS?Number

6628-04-2

Density

1.169 g/cm3

Melting Point

162-166 °C(lit.)

Boiling Point

327.4 °C at 760 mmHg

Flash Point

178 °C

Vapor Pressure

0.000203mmHg at 25°C

Refractive Index

1.7080 (estimate)

HS CODE

29334900

PSA

38.91000

LogP

2.70660

Pka

9.40±0.50(Predicted)

3.What are another words for 4-AMINO-2-METHYLQUINOLINE ?

Synonyms?for?4-AMINO-2-METHYLQUINOLINE 6628-04-2:NSC 60281;4-Aminoquinaldine;4-Amino-2-methylquinoline;2-Methyl-4-quinolinamine;2-Methyl-4-aminoquinoline;(2-Methylquinolin-4-yl)amine;Quinaldine,4-amino- (6CI,7CI,8CI);4-Quinaldinamine;

4.What is the molecular formula of 4-AMINO-2-METHYLQUINOLINE?

The chemical formula of ?4-AMINO-2-METHYLQUINOLINE is?C10H10N2 which containing 10 Carbon atoms,10 Hydrogen atoms and 2 Nitrogen atoms,and the molecular weight of??4-AMINO-2-METHYLQUINOLINE?is 158.203.

5.What is 4-AMINO-2-METHYLQUINOLINE (6628-04-2) used for?

InChI:InChI=1/C10H10N2/c1-7-6-9(11)8-4-2-3-5-10(8)12-7/h2-6H,1H3,(H2,11,12)/p+1

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6.Buy 4-AMINO-2-METHYLQUINOLINE with the best price .

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