Details
Chinese Factory Supply Wholesale Mexiletine hydrochloride 5370-01-4 with Cheap Price We supply high quality Mexiletine hydrochloride (CAS 5370-01-4), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the Mexiletine hydrochloride ?
Mexiletine hydrochloride is white to off-white solid, while it's Molecular Formula is C11H17NO. HCl. antipsychotic
What is the CAS number for Mexiletine hydrochloride ?
The CAS number of Mexiletine hydrochloride is 5370-01-4.
More information of Mexiletine hydrochloride 5370-01-4 are:
|
Synonyms |
2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride (9CI);Ethylamine, 1-methyl-2-(2,6-xylyloxy)-,hydrochloride (7CI,8CI);Katen;Ko 1173;Ko 1173Cl;Mexiletinehydrochloride;Mexilitene;Mexitil;Ritalmex; |
|
CAS?Number |
5370-01-4 |
|
Molecular Formula |
C11H17NO. HCl |
|
Molecular Weight |
215.723 |
|
Density |
0.979 g/cm3 |
|
Melting Point |
200-203 °C |
|
Boiling Point |
271.5 °C at 760 mmHg |
|
Flash Point |
112.2 °C |
|
HS CODE |
2922190900 |
|
PSA |
35.25000 |
|
LogP |
3.53170 |
|
Pka |
9.0(at 25℃) |
What is Mexiletine hydrochloride (5370-01-4) used for?
Mexiletine is a voltage-gated sodium channel blocker and class Ib antiarrhythmic agent that preferentially binds to open/inactive channels. It inhibits aconitine-induced dysrhythmias in mice with ED50 values of 57 and 107 mg/kg for intraperitoneal and oral administration, respectively. Mexiletine decreases or inhibits conduction across the Purkinje fiber-muscle junction, shortens action potential duration, and decreases the refractory period when used at concentrations less than 5 μg/ml in isolated canine Purkinje fiber and ventricular muscle preparations.
InChI:InChI=1/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H
Articles related to Mexiletine hydrochloride:
|
Article |
Source |
|
Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes |
Cashman, John R.,Ryan, Daniel,McKeithan, Wesley L.,Okolotowicz, Karl,Gomez-Galeno, Jorge,Johnson, Mark,Sampson, Kevin J.,Kass, Robert S.,Pezhouman, Arash,Karagueuzian, Hrayr S.,Mercola, Mark , p. 5384 - 5403 (2021/05/29) |
|
Production method of mexiletine hydrochloride |
- Paragraph 0031; 0041-0053, (2018/04/02) |
How to get the best price on Mexiletine hydrochloride?
CHANGCHUN WEIERSI IMPORT AND EXPORT TRADE CO.,LTD is a quality supplier and manufacturer of Mexiletine hydrochloride . You can buy high quality, low price Mexiletine hydrochloride 5370-01-4 here. Contact us.